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pentobarbital will lessen the extent or result of efavirenz by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Small/Importance Unidentified.pentobarbital will reduce the extent or effect of ethotoin by influencing hepatic enzyme CYP2C9/ten metabolism. Use Caution/Keep an eye on.pentobarbital decreases amounts of vandetanib by affecting hepa